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Week Thu. 13 Fri. 14 List

	Thu. 13	Fri. 14
08:00 09:00 10:00 11:00 12:00 13:00 14:00 15:00 16:00 17:00 18:00 19:00 20:00 21:00	Registration 12:00 - 13:15 (1h15) Registration Registration in the hall of the Hexagone Welcome Introduction 13:15 - 13:30 (15min) Welcome Introduction Auditorium Opening lecture KEYNOTE : MYST-family acetyltransferases in gene expression, genome stability and disease 13:30 - 14:15 (45min) Opening lecture KEYNOTE : MYST-family acetyltransferases in gene expression, genome stability and disease Auditorium Jacques Côté (CHU de Québec-Université Laval, Québec, CA) https://cms2024.sciencesconf.org/data/program/Jacques_Cote.pdf Chromatin Meets South Guest speaker : Paternal Epigenetic Transgenerational Inheritance of metabolic disease susceptibility in mice. .Biallelic gain of a permissive chromatin signature precedes productive maternal enhancer-promoter interaction at the Zim1 imprinted gene during neural commitment Genome resilience safeguards functional chromatin states Non-coding RNAs in the control of imprinted chromosomal domains Company 14:15 - 15:55 (1h40) Chromatin Meets South Auditorium Epigenetic Inheritance & Imprinting 14:15 - 14:45 (30min) Guest speaker : Paternal Epigenetic Transgenerational Inheritance of metabolic disease susceptibility in mice. Valérie GRANDJEAN (C3M, Nice) https://cms2024.sciencesconf.org/data/program/Valerie_Grandjean.pdf 14:45 - 15:05 (20min) .Biallelic gain of a permissive chromatin signature precedes productive maternal enhancer-promoter interaction at the Zim1 imprinted gene during neural commitment Franck Court https://cms2024.sciencesconf.org/data/program/Philippe_Arnaud.CMS_2024_Rengifo_Rojas.pdf 15:05 - 15:25 (20min) Genome resilience safeguards functional chromatin states Flora Paldi https://cms2024.sciencesconf.org/data/program/Flora_Paldi.pdf 15:25 - 15:45 (20min) Non-coding RNAs in the control of imprinted chromosomal domains Robert Feil https://cms2024.sciencesconf.org/data/program/Robert_Feil.pdf 15:45 - 15:55 (10min) Company Active Motif Coffee break 15:55 - 16:15 (20min) Coffee break Hall d’exposition Chromatin Meets South Guest speaker : XIST loss in Human Mammary Epithelial Cells, a model of epigenetic priming during tumor initiation. Specificity of the family of lysine methyltransferases SUV4-20H in prostate cancer Three-dimensional genome organization during TGFB-induced transcription requires nuclear microRNA and G-quadruplexes 16:15 - 17:25 (1h10) Chromatin Meets South Auditorium Epigenetics & Cancer I 16:15 - 16:45 (30min) Guest speaker : XIST loss in Human Mammary Epithelial Cells, a model of epigenetic priming during tumor initiation. Christophe Ginestier (CRCM, Marseille) https://cms2024.sciencesconf.org/data/program/christophe_Ginestie.pdf 16:45 - 17:05 (20min) Specificity of the family of lysine methyltransferases SUV4-20H in prostate cancer Hiba Daher https://cms2024.sciencesconf.org/data/program/Hiba_Daher.pdf 17:05 - 17:25 (20min) Three-dimensional genome organization during TGFB-induced transcription requires nuclear microRNA and G-quadruplexes Guillermo Barreto https://cms2024.sciencesconf.org/data/program/Guillermo_Barreto.pdf Refreshment Chromatin Meets South Guest speaker : Characterizing intergenic transcription at RNA polymerase II binding sites in normal and cancer tissues Mutational synergy with CREBBP loss in lymphomagenesis identified through forward insertional mutagenesis in a new DLBCL mouse model Company 17:25 - 17:40 (15min) Refreshment Hall d’exposition 17:35 - 18:40 (1h05) Chromatin Meets South Auditorium Epigenetics & Cancer II 17:40 - 18:10 (30min) Guest speaker : Characterizing intergenic transcription at RNA polymerase II binding sites in normal and cancer tissues Benoit BALLESTER (TAGC, Marseille) https://cms2024.sciencesconf.org/data/program/Benoit_Ballester.pdf 18:10 - 18:30 (20min) Mutational synergy with CREBBP loss in lymphomagenesis identified through forward insertional mutagenesis in a new DLBCL mouse model Nathalie Sakakini https://cms2024.sciencesconf.org/data/program/Nathalie_Sakakini.pdf 18:30 - 18:40 (10min) Company NEB Dinner 18:40 - 21:30 (2h50) Dinner Restaurant universitaire Luminy	Coffee break 8:30 - 9:00 (30min) Coffee break Hall d’exposition Chromatin Meets South Guest speaker : Secondary DNA structures contribute to promoter activity as nucleosome exclusion modules Unraveling a novel dual-function regulatory element showing epistatic interaction with a variant that escapes genome-wide association studies Degron-induced inactivation of H2A.Z isoforms in mammalian cells Company 9:00 - 10:20 (1h20) Chromatin Meets South Auditorium Control of Gene Expression 9:00 - 9:30 (30min) Guest speaker : Secondary DNA structures contribute to promoter activity as nucleosome exclusion modules Jean-Christophe ANDRAU(IGMM, Montpellier) https://cms2024.sciencesconf.org/data/program/Jean_Christophe_Andrau.pdf 9:30 - 9:50 (20min) Unraveling a novel dual-function regulatory element showing epistatic interaction with a variant that escapes genome-wide association studies Mathieu Adjemout https://cms2024.sciencesconf.org/data/program/Mathieu_Adjemout.pdf 9:50 - 10:10 (20min) Degron-induced inactivation of H2A.Z isoforms in mammalian cells Didier Trouche https://cms2024.sciencesconf.org/data/program/Didier_Trouche.pdf 10:10 - 10:20 (10min) Company Covaris Coffee break Chromatin Meets South Guest speaker : Chromosome organisation for meiotic recombination in mice Embryonic cell senescence at the origin of the cohesinopathy Cornelia de Lange syndrome Evidence that nucleosome arrays antagonise the folding of genomic DNA into condensed mitotic chromosomes by loop-extruding condensin RNA profiling of molecular crowed nuclear micro-environments Company 10:20 - 10:40 (20min) Coffee break Hall d’exposition 10:35 - 12:20 (1h45) Chromatin Meets South Auditorium Chromosome Organization 10:40 - 11:10 (30min) Guest speaker : Chromosome organisation for meiotic recombination in mice Corinne GREY (IGH, Montpellier) https://cms2024.sciencesconf.org/data/program/Coriine_Grey.pdf 11:10 - 11:30 (20min) Embryonic cell senescence at the origin of the cohesinopathy Cornelia de Lange syndrome Michel Puceat https://cms2024.sciencesconf.org/data/program/Michel_Puceat.pdf 11:30 - 11:50 (20min) Evidence that nucleosome arrays antagonise the folding of genomic DNA into condensed mitotic chromosomes by loop-extruding condensin Dana El Meouch https://cms2024.sciencesconf.org/data/program/Dana_El_Meouch.pdf 11:50 - 12:10 (20min) RNA profiling of molecular crowed nuclear micro-environments Thierry Forné https://cms2024.sciencesconf.org/data/program/Thierry_Forne.pdf 12:10 - 12:20 (10min) Company Diagenode Lunch 12:20 - 13:50 (1h30) Lunch Restaurant universitaire Luminy Chromatin Meets South Guest speaker : Transcriptional repression accounts for RNA:DNA hybrid accumulation at DNA Double Strand breaks Deciphering chromatin dynamic changes along cell cycle phases. Neural network and kinetic modelling of human genome replication reveal replication origin locations and strengths Coffee break 13:50 - 15:10 (1h20) Chromatin Meets South Auditorium Genome dynamics & stability 13:50 - 14:20 (30min) Guest speaker : Transcriptional repression accounts for RNA:DNA hybrid accumulation at DNA Double Strand breaks Aline Marnef (CBI, Toulouse) https://cms2024.sciencesconf.org/data/program/Aline_marnef.pdf 14:20 - 14:40 (20min) Deciphering chromatin dynamic changes along cell cycle phases. Martin Rey-Millet https://cms2024.sciencesconf.org/data/program/Martin_Rey_Millet.pdf 14:40 - 15:00 (20min) Neural network and kinetic modelling of human genome replication reveal replication origin locations and strengths Jean-Michel Arbona https://cms2024.sciencesconf.org/data/program/Jean_Michel_Arbona.pdf 15:00 - 15:30 (30min) Coffee break Hall d’exposition Chromatin Meets South Guest speaker : The epigenetic and transcriptional interplay between L1 retrotransposons and their integration sites The Interplay Between SUMOylation & DNA Methylation in the Control of Transposable Elements in Acute Myeloid Leukemia . 15:30 - 16:30 (1h) Chromatin Meets South Auditorium Transposable Elements 15:30 - 16:00 (30min) Guest speaker : The epigenetic and transcriptional interplay between L1 retrotransposons and their integration sites Gael Cristofari (IRCAN, Nice) https://cms2024.sciencesconf.org/data/program/Gael_Cristofari.pdf 16:00 - 16:20 (20min) The Interplay Between SUMOylation & DNA Methylation in the Control of Transposable Elements in Acute Myeloid Leukemia Mays Aqrouq https://cms2024.sciencesconf.org/data/program/Mays_Aqrouq.pdf 16:20 - 16:30 (10min) . CONCLUSIONS

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